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Advances in Drug Therapies for Fallopian Tube Cancer

Dr. Muralinath. E, Tanuz Kumar. A., Mumtesh Kumar. S, Sudhir Kumar, Aman Kamboj S, Kalyan C., Archana Jain, Guruprasad M.

Abstract


Fallopian tube cancer is a rare but serious gynecological malignancy that frequently poses challenges regarding diagnosis and treatment. Platinum_ based chemotherapy is the standard first _ line treatment for Fallopian tube cancer partipates along with a union of drugs such as cisplatin as well as paclitaxel. These agents perform by interfering with the DNA od rapidly dividing cancer cells, stopping their growth and causing cell death. Poly ( ADP _ ribose) polymerase ( parp) inhibitors represent a important advance regarding the treatment of Fallopian tube cancer, particularly for patients with specific gene mutations such as BRCA 1 or BRCA 2. PARP inhibitors namely olaparib and niraparib, target the DNA repair process particularly in cancer cells, resulting in their demise. Immuno therapy has attracted lot if attention regarding cancer treatment across various types, along with Fallopian tube cancer. Bevacizumab is an anti ,_ angoogenic drug approved for use along with chemotherapy for treatment of Fallopian tube cancer. It performs by stopping VEGF. A protective participated in angiogenesis, thereby limiting the blood supply to tumors and impeding their growth. Finally it is concluded that an advancements in drug therapies gor Fallopian tube cancer have opened new avenues for personalized and targeted treatments.


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References


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