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An Important Parameters of Methemoglobinemia Include Symptoms, Clinical Management and Treatment

Srinivas G., Ramanjaneyulu D. V., Muralinath E., Guruprasad M., Sravani Pragna K., Manjari P., Sony Sharlet E., T. Nikhil, V.Yaswanth Sai, D. Kusuma Latha, R. Faith Rani, P. Megha Varna

Abstract


Ferri-iron of methemoglobin (MetHb) is a rare disorder associated with the oxidation of divalent ferro-iron of hemoglobin (Hb). Both acquired and hereditary processes can result from methemoglobinemia. The most prevalent types are acquired ones, primarily as a result of exposure to chemicals that directly or indirectly oxidize Hb. Inherited forms are due either to autosomal recessive variants in the CYB5R3 gene or to autosomal dominant variants in the globin genes, collectively termed as HbM disease.


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